Astellas Pharma, a pharmaceutical company headquartered in Japan, announced on Jan. 13, 2019 that it is entering into a co-development and co-commercialization agreement for cell therapies with United Kingdom-based Adaptimmune Therapeutics in a deal worth potentially up to $897.5 million.
Access Accelerated is a first-of-its-kind, multi-stakeholder collaboration focused on improving...The “Story” section contains contents focused on “hero”: people (patients, employees, scientists, etc. Further details governing co-development and co-commercialization will be articulated in a product-specific commercialization agreement.The impact of this transaction on Astellas’ financial results in the fiscal year ending March 31, 2020 will be limited. The companies will each have a co-exclusive licence covering the co-development and co-commercialization of the product candidates within the field of T-cell therapy.
"Astellas positions immuno-oncology as one of its strategic areas of primary focus, and it is engaged in the development of novel therapies for cancer patients using a new modality/technology," stated Naoki Okamura, Representative Director Corporate Executive Vice President, Chief Strategy Officer and Chief Financial Officer, Astellas. Finally, Adaptimmune would receive tiered royalties on net sales in the mid-single to mid-teen digits.Under the terms of the agreement, Astellas may receive up to $552.5 million, including: In addition, Astellas would receive tiered royalties on net sales in the mid-single to mid-teen digits.To the extent that Astellas and Adaptimmune co-develop and co-commercialize any T-cell therapy, they will equally share the costs of such co-development and co-commercialization, with the resulting profits from co-commercialization also shared equally. If a candidate is developed by one company only, the appropriate licences will become exclusive to the continuing party. Thank you for visiting the Astellas Pharma Inc. Website. If you feel the same, we’d like to hear from you. Sorry, you need to enable JavaScript to visit this website. Astellas will have sole rights to develop and commercialize these products, subject to necessary licenses and the payment of milestones and royalties.Under the terms of the agreement, Adaptimmune may receive up to $897.5 million in payments, including:In addition, Adaptimmune will receive research funding of up to $7.5 million per year. Rawcliffe states the deal with Astellas came about because of the progress that has been made.
Astellas participates in Access Accelerated.
We will continue to dedicate our efforts in delivering novel treatments for diseases with high unmet medical needs, pursuing cutting-edge science and technological advances.”“We are delighted to establish this significant co-development partnership with Astellas, which builds upon and substantially extends an existing collaboration focused on gene editing of iPSC cells,” said Helen Tayton-Martin, Adaptimmune’s Chief Business Officer and Co-Founder. Adaptimmune has been collaborating with Universal Cells since 2015 on development of gene-edited iPSC cell lines, for which Adaptimmune has rights to develop and commercialize resulting T-cell therapy products using its proprietary process for generating T cells from stem cells without the use of feeder cell lines. We believe that to be successful, it is essential to look to the future and consider how we can contribute to creating and delivering on the promise of cell therapy for patients. Get in Touch ), scientific innovation and social...Review our consolidated business results, forecasts and financial data, etc.This website contains information about products that may not be available in all countries, or may be available under different trademarks, for different indications, or in different dosages. Cell-based therapeutics have tremendous potential to satisfy unmet patient needs across a broad range of disease areas. Nothing contained herein should be considered a solicitation, promotion or advertisement for any drug including the ones under development on this web site.Any information on the products contained herein is not intended to provide medical advice nor should be used as a substitute for the advice provided by your physician or other healthcare provider.Over the last few years, we have acquired and developed the means to create a broad portfolio of different cell types. Astellas, headquartered in Japan, is bolstering its manufacturing capabilities for cell and gene therapies, in line with its R&D and investment push in the space. Access Accelerated is a first-of-its-kind, multi-stakeholder collaboration focused on improving...The “Story” section contains contents focused on “hero”: people (patients, employees, scientists, etc. Astellas participates in Access Accelerated. - Agreement covers the co-development and co-commercialization of up to three T-cell therapies -- Agreement leverages Astellas’ Universal Donor Cell Platform and Adaptimmune’s stem-cell derived allogeneic T-cell platform -- Astellas will pay Adaptimmune an upfront payment, research funding, development and commercial milestones, and royalties on net sales on co-commercialized products - It brings together highly complementary skills and expertise across the two organizations, and will enable the accelerated development of new, off-the-shelf T-cell therapy products for people with cancer.”Astellas will also have the right to select two targets and develop allogeneic cell therapy candidates independently. Sorry, you need to enable JavaScript to visit this website.
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